Research on hydrophobicity of electrospun Fe3O4/PVDF nanofiber membranes under different preparation conditions

Abstract

Preparation condition can affect the structure and the properties of nanofiber membrane. In order to explore suitable conditions to prepare the Fe₃O₄/PVDF nanofiber membrane with good hydrophobicity, the hydrophobicity of Fe₃O₄/PVDF nanofiber membranes obtained by electrospinning was investigated by changing preparation conditions like weight percentage of Fe₃O₄ nanoparticles, blending quality concentration of poly (vinylidene fluoride) (PVDF) and Fe₃O₄ nanoparticles, and positive voltage. And the variations of hydrophobicity of Fe₃O₄/PVDF nanofiber membranes modified by 1H, 1H, 2H, 2H-perfluorodecyl trimethoxysilane were studied. The results show that the hydrophobicity of Fe₃O₄/PVDF nanofiber membranes has changed under different preparation conditions. The contact angles of samples increased after a modification by 1H, 1H, 2H, 2H-perfluorodecyl trimethoxysilane, which indicates that the hydrophobicity of Fe₃O₄/PVDF nanofiber membranes has been enhanced.     

Biomimetic Engineering of a Scavenger‐Free Nitric Oxide‐Generating/Delivering System to Enhance Radiation Therapy

Nitric oxide (NO) is a potent tumor‐cell radiosensitizer but it can be readily scavenged by hemoglobin (Hb) in vivo. A biomimetic incubator that can generate and deliver NO in a scavenger (Hb)‐free environment to enhance its radiosensitizing effect to maximize its efficacy in radiotherapy is proposed. This NO incubator comprises a poly(lactic‐co‐glycolic acid) (PLGA) hollow microsphere (HM) that contains an NO donor (NONOate) and a surfactant molecule (sodium caprate, SC) in its aqueous core. In acidic tumorous environments, the PLGA shell of the HM allows the penetration of protons from the outside, activating the hydrolytic cleavage of NONOate, spontaneously generating NO bubbles, which are immediately trapped/stabilized by SC. The SC‐stabilized NO bubbles in the HM are then squeezed through the spaces of its PLGA matrices by the elevated internal pressure. Upon leaving the HM, the entrapped NO molecules may passively diffuse through their SC‐stabilized/protected layer gradually to the tumor site, having a long‐lasting radiosensitizing effect and inhibiting tumor growth. The entire process of NO generation and delivery is conducted in a scavenger (Hb)‐free environment, mimicking the development of young ovoviviparous fish inside their mothers' bodies in the absence of predators before birth.     

Formation of a protective layer against corrosion on Mg alloy via alkali pretreatment followed by vanillic acid treatment

Although Mg alloy possesses high specific strength, low density, and good biocompatibility, poor corrosion resistance hinders its further applications. In the present study, an innovative protective layer against corrosion was prepared on the AZ31 Mg alloy via alkali pretreatment followed by vanillic acid treatment. The alkali pretreatment supplied –OH for the AZ31 Mg alloy surface to react with vanillic acid. The vanillic acid treatment played a crucial role in enhancing the corrosion resistance due to the excellent ability to act as a barrier and retard aqueous solution penetration, which effectively isolated the underlying Mg alloy from the corrosive environment. The corrosion current density of alkali and vanillic acid-treated Mg alloy (AZ31V) almost showed two orders of magnitude lower values in comparison with that of the AZ31 Mg alloy, and the corrosion potential of AZ31V Mg alloy increased from −1.41 to −1.25 V. The immersion tests proved that there was no occurrence of severe corrosion. Hence, the alkali pretreatment and vanillic acid treatment may represent a promising method to improve the corrosion resistance of Mg alloy.     

汽车保险杠激光打孔机的研制

由激光加工系统、旋转工作台机构和PLC控制系统组成,针对传统专用打孔机打孔样式单一,工作效率、精度不高的问题,实现光、机、电三者的紧密配合自动化打孔。采用飞行光路的加工方案,能够对不同车型保险杠的不同孔型进行打孔加工。打孔机中的激光加工系统具有灵活、稳定和高精度等优点。     

AppFusion: Interactive Appearance Acquisition Using a Kinect Sensor

We present an interactive material acquisition system for average users to capture the spatially varying appearance of daily objects. While an object is being scanned, our system estimates its appearance on‐the‐fly and provides quick visual feedback. We build the system entirely on low‐end, off‐the‐shelf components: a Kinect sensor, a mirror ball and printed markers. We exploit the Kinect infra‐red emitter/receiver, originally designed for depth computation, as an active hand‐held reflectometer, to segment the object into clusters of similar specular materials and estimate the roughness parameters of BRDFs simultaneously. Next, the diffuse albedo and specular intensity of the spatially varying materials are rapidly computed in an inverse rendering framework, using data from the Kinect RGB camera. We demonstrate captured results of a range of materials, and physically validate our system.     

生物素标记的布鲁菌多克隆抗体的制备

目的制备生物素标记的兔抗牛种布鲁菌544A多克隆抗体,并进行鉴定。方法复苏并扩大培养牛种布鲁菌544A,灭活后制备灭活疫苗,经背部皮下多点注射免疫新西兰大白兔,5次免疫后,经心脏采血,分离血清,采用硫酸铵盐析法对血清中的多克隆抗体进行粗提,再通过蛋白亲和柱层析法对抗体进一步纯化,利用SDS-PAGE分析抗体的纯度,间接ELISA法检测抗体的效价和特异性,Bradford法检测抗体的蛋白含量,并利用生物素对抗体进行标记。结果制备的牛种布鲁菌544A的兔多克隆抗体纯度较高,效价为1:256 000,特异性较好,蛋白含量为2.83 mg/ml,每摩尔蛋白中标记的生物素摩尔数为3.09。结论成功制备了生物素标记的牛种布鲁菌多克隆抗体,为下一步研制牛种布鲁菌免疫检测试剂盒奠定了物质基础。     

牵引逆变器IGBT风冷散热试验及仿真平台搭建

IGBT散热性能是影响高速动车组在行驶过程中安全性、可靠性及动力性的重要因素。本文以某出口铰接车牵引变流器箱为试验研究载体,研制了专用风冷散热试验台;同时运用仿真软件Flotherm进行了仿真计算,通过实物试验与仿真计算的对比研究,验证了仿真计算的可行性。